also drive other qubits due to crosstalk arising from capacitive coupling and wavefunction overlap in systems with closely spaced transition frequencies. Crosstalk and frequency crowding increase errors during simultaneous single-qubit operations relative to isolated gates, thus forming a major bottleneck for scaling superconducting quantum processors. In this work, we combine model-based qubit frequency optimization with pulse shaping to demonstrate crosstalk error mitigation in single-qubit gates on a 49-qubit superconducting quantum processor. We introduce and experimentally verify an analytical model of simultaneous single-qubit gate error caused by microwave crosstalk that depends on a given pulse shape. By employing a model-based optimization strategy of qubit frequencies, we minimize the crosstalk-induced error across the processor and achieve a mean simultaneous single-qubit gate fidelity of 99.96% for a 16-ns gate duration, approaching the mean individual gate fidelity. To further reduce the simultaneous error and required qubit frequency bandwidth on high-crosstalk qubit pairs, we introduce a crosstalk transition suppression (CTS) pulse shaping technique that minimizes the spectral energy around transitions inducing leakage and crosstalk errors. Finally, we combine CTS with model-based frequency optimization across the device and experimentally show a systematic reduction in the required qubit frequency bandwidth for high-fidelity simultaneous gates, supported by simulations of systems with up to 1000 qubits. By alleviating constraints on qubit frequency bandwidth for parallel single-qubit operations, this work represents an important step for scaling towards larger quantum processors.