we experimentally investigate the emergent ℤ2 gauge invariance in a 1D superconducting circuit with 10 transmon qubits. By precisely adjusting the staggered longitude and transverse fields to each qubit, we construct an effective Hamiltonian containing a LGT and gauge-broken terms. The corresponding matter sector can exhibit localization, and there also exist a 3-qubit operator, of which the expectation value can retain nonzero for long time in a low-energy regime. The above localization can be regarded as confinement of the matter field, and the 3-body operator is the ℤ2 gauge generator. Thus, these experimental results demonstrate that, despite the absent of gauge structure in the effective Hamiltonian, ℤ2 gauge invariance can still emerge in the low-energy regime. Our work paves the way for both theoretically and experimentally studying the rich physics in quantum many-body system with an emergent gauge invariance.