Hamiltonians may also have real eigenvalues. Systems described by such effective -symmetric Hamiltonians have been realized in experiments using coupled systems with balanced loss (dissipation) and gain (amplification), and their corresponding classical dynamics has been studied. A -symmetric system emerging from a quantum dynamics is highly desirable, in order to understand what -symmetry and the powerful mathematical and physical concepts around it will bring to the next generation of quantum technologies. Here, we address this need by proposing and studying a circuit-QED architecture that consists of two coupled resonators and two qubits (each coupled to one resonator). By means of external driving fields on the qubits, we are able to tune gain and losses in the resonators. Starting with the quantum dynamics of this system, we show the emergence of the -symmetry via the selection of both driving amplitudes and frequencies. We engineer the system such that a non-number conserving dipole-dipole interaction emerges, introducing an instability at large coupling strengths. The -symmetry and its breaking, as well as the predicted instability in this circuit-QED system can be observed in a transmission experiment.