system’s observable and converts the information gain into work via feedback control. Recent developments have elucidated the relationship between the acquired information and the entropy production and generalized the second law of thermodynamics and the fluctuation theorems. Here we extend the scope to a system subject to quantum fluctuations by exploiting techniques in superconducting circuit quantum electrodynamics. We implement Maxwell’s demon equipped with coherent control and quantum nondemolition projective measurements on a superconducting qubit, where we verify the generalized integral fluctuation theorems and demonstrate the information-to-work conversion. This reveals the potential of superconducting circuits as a versatile platform for investigating quantum information thermodynamics under feedback control, which is closely linked to quantum error correction for computation and metrology.