circuits. In some aspects, these two platforms are dual to one another: superconducting qubits are more easily coupled but are relatively large among quantum devices (∼mm), while electrostatically-confined electron spins are spatially compact (∼μm) but more complex to link. Here we combine beneficial aspects of both platforms in the Andreev spin qubit: the spin degree of freedom of an electronic quasiparticle trapped in the supercurrent-carrying Andreev levels of a Josephson semiconductor nanowire. We demonstrate coherent spin manipulation by combining single-shot circuit-QED readout and spin-flipping Raman transitions, finding a spin-flip time TS=17 μs and a spin coherence time T2E=52 ns. These results herald a new spin qubit with supercurrent-based circuit-QED integration and further our understanding and control of Andreev levels — the parent states of Majorana zero modes — in semiconductor-superconductor heterostructures.