nonreciprocal interaction and entanglement between two qubits by combining coherent and dissipative couplings in a superconducting platform, where two coherently coupled transmon qubits simultaneously interact with a transmission line waveguide. The coherent interaction between the transmon qubits can be achieved via capacitive coupling or via an intermediary cavity mode, while the dissipative interaction is induced by the transmission line via reservoir engineering. With high tunability of superconducting qubits, their positions along the transmission line can be adjusted to tune the dissipative coupling, enabling to tailor reciprocal and nonreciprocal interactions between the qubits. A fully nonreciprocal interaction can be achieved when the separation between the two qubits is (4n+3)λ0/4, where n is an integer and λ0 is the photon wavelength. This nonreciprocal interaction enables the generation of nonreciprocal entanglement between the two transmon qubits. Furthermore, applying a drive field to one of the qubit can stabilize the system into a nonreciprocal steady-state entangled state. Remarkably, the nonreciprocal interaction in this work does not rely on the presence of nonlinearity or complex configurations, which has more potential applications in designing nonreciprocal quantum devices, processing quantum information, and building quantum networks.