our focus centers on designing variational quantum algorithms within the analog paradigm. This involves optimizing parameters that directly control pulses, driving quantum states towards target states without the necessity of compiling a quantum circuit. In this work, we introduce pulse-based variational quantum optimization (PBVQO) as a hardware-level framework. We illustrate the framework by optimizing external fluxes on superconducting quantum interference devices, effectively driving the wave function of this specific quantum architecture to the ground state of an encoded problem Hamiltonian. Given that the performance of variational algorithms heavily relies on appropriate initial parameters, we introduce a global optimizer as a meta-learning technique to tackle a simple problem. The synergy between PBVQO and meta-learning provides an advantage over conventional gate-based variational algorithms.