state transitions which limit the speed and fidelity of such operations. In this work, we systematically investigate such transitions in a fixed-frequency qubit subjected to microwave drives spanning a 9 GHz frequency range. We identify the physical origins of these transitions and classify them into three categories. (1) Resonant energy exchange with parasitic two-level systems, activated by drive-induced ac-Stark shifts, (2) multi-photon transitions to non-computational states, intrinsic to the circuit Hamiltonian, and (3) inelastic scattering processes in which the drive causes a state transition in the superconducting circuit, while transferring excess energy to a spurious electromagnetic mode or two-level system (TLS) material defect. We show that the Floquet steady-state simulation, complemented by an electromagnetic simulation of the physical device, accurately predicts the observed transitions that do not involve TLS. Our results provide a comprehensive classification of these transitions and offer mitigation strategies through informed choices of drive frequency as well as improved circuit design.