have been proposed to detect and manipulate Majorana zero modes using superconducting qubits. However, manipulating and reading the Majorana zero modes must be kept in the time window of quasiparticle poisoning. In this work, we study the problem of quasiparticle poisoning in a split transmon qubit containing hybrid Josephson junctions involving Majorana zero modes. We show that Majorana coupling will cause parity mixing and 4{\pi} Josephson effect. In addition, we obtained the expression of qubit parameter-dependent parity switching rate and demonstrated that quasiparticle poisoning can be greatly suppressed by reducing E_J/E_C via qubit design.